C50.922 ICD-10-CM Code: Malignant neoplasm of unspecified site of left male breast
HCC Buddy Code Card
Digital ICD-10 code-book layout with official code detail, always-visible risk models, Code Trumping, and Buddy coding guidance.
FY 2026 Apr update / Neoplasms (C00-D49) / Malignant neoplasms of breast (C50)
C50.922
Billable / SpecificICD-10-CMOfficial ICD-10-CMCodebook guidanceMalignant neoplasm of unspecified site of left male breast
This code describes cancer that has developed in the left breast of a male patient, but the specific location within the breast tissue has not been documented. Male breast cancer is rare but requires the same treatment and monitoring as female breast cancer.

Buddy Insight
Malignant neoplasm of unspecified site of left male breast captures a left-sided breast cancer in a male patient.
CMS-HCC V28
00
RAF 0
CMS-HCC V24
MappedHCC 12
RAF 0.150
ACA/HHS
00
RAF 0
ESRD/PACE
MappedHCC 12
RAF 0.0
RXHCC
MappedHCC 22
RAF 0.0
Code Trumping
Basket needed
Code Book Path
Inclusion Terms
OfficialICD-10-CM does not list inclusion terms for C50.922 in this effective period.
Excludes 2
OfficialICD-10-CM does not list Excludes 2 notes for C50.922 in this effective period.
Related Child Codes
Includes
OfficialICD-10-CM does not list Includes notes for C50.922 in this effective period.
Excludes 1
OfficialICD-10-CM does not list Excludes 1 notes for C50.922 in this effective period.
Code First
OfficialICD-10-CM does not list Code First sequencing instructions for C50.922 in this effective period.
Use Additional
OfficialICD-10-CM does not list Use Additional Code instructions for C50.922 in this effective period.
Code Also
OfficialICD-10-CM does not list Code Also instructions for C50.922 in this effective period.
Buddy Documentation Tip
MEAT Support
Audit Caution
Common Mistakes
Last updated: FY2026 ICD-10-CM Apr update, Apr 1, 2026 through Sep 30, 2026. CMS-HCC V28 is 100% phased in for payment year 2026.
Is C50.922 an HCC code?
Yes. C50.922 maps to Breast, Prostate, and Other Cancers and Tumors under the V24 model but is not retained in V28.
HCC Category Mapping
RAF weights shown are the community, non-dual, aged base weights from the CMS risk adjustment model file. Actual per-patient RAF contribution depends on member segment, interactions, and the model year used by the payer. V28 is the CMS-HCC model phased in over payment years 2024–2026; V24 remains in use during the transition and for historical data.
MEAT Criteria for C50.922
For C50.922to count as a valid HCC diagnosis in a given encounter, the provider's documentation must show MEAT: Monitor, Evaluate, Assess, or Treat. A diagnosis from a prior year does not carry forward automatically, it has to be re-documented and supported each calendar year.
- MMonitor: signs, symptoms, disease progression, or lab trending documented in the note
- EEvaluate: test results, medication response, or physical findings reviewed by the provider
- AAssess: explicit mention in the assessment or plan with acknowledgment of status
- TTreat: medication, referral, procedure, therapy, or counseling tied to the diagnosis
Only one of M/E/A/T is required to support the code, but the documentation must be specific enough to show that the provider actually addressed C50.922 during that encounter, not just copy-forwarded from a problem list.
What This Code Means
C50.922 is the ICD-10-CM diagnosis code for malignant neoplasm of unspecified site of left male breast. This code describes cancer that has developed in the left breast of a male patient, but the specific location within the breast tissue has not been documented. Male breast cancer is rare but requires the same treatment and monitoring as female breast cancer. C50.922 sits in the ICD-10-CM chapter for neoplasms (c00-d49), within the section covering malignant neoplasms of breast (c50).
Under the older CMS-HCC V24 model, C50.922 maps to Breast, Prostate, and Other Cancers and Tumors (HCC 12) with a community, non-dual, aged base RAF weight of 0.150. V28 is the CMS-HCC risk adjustment model that reached 100% phase-in for payment year 2026, replacing V24 which was used during the PY2024–PY2025 transition.
Verify documentation specifies the cancer is in the left breast and that the site is truly unspecified; if a specific quadrant or location is documented, use a more specific C50.9 code variant. Because C50.922 maps to a payment HCC, the provider's documentation must satisfy MEAT criteria (Monitor, Evaluate, Assess, or Treat) for the encounter to count toward the patient's Medicare Advantage risk adjustment score. When documentation is ambiguous, coders should issue a provider query rather than assume the highest-specificity variant.
HCC Buddy maintains structured V28 and V24 mapping, RAF weights, and MEAT documentation criteria for C50.922 sourced directly from the CMS-HCC risk adjustment model files and the CMS ICD-10-CM code set.
Coding Tips
- •Verify documentation specifies the cancer is in the left breast and that the site is truly unspecified; if a specific quadrant or location is documented, use a more specific C50.9 code variant
- •Ensure this code is used only for male patients; female breast cancer uses different C50 codes (C50.1-C50.9 with different laterality indicators)
Clinical Significance
Malignant neoplasm of unspecified site of left male breast captures a left-sided breast cancer in a male patient. Male breast cancer has distinct epidemiological features including association with BRCA2 mutations, Klinefelter syndrome, and radiation exposure. Left-sided predominance has been observed in some studies, making laterality documentation clinically relevant.
Documentation Requirements
- ✓Confirmed male patient sex
- ✓Laterality documented as left breast
- ✓Histological type (invasive ductal carcinoma most common)
- ✓TNM staging and grade
- ✓Receptor status documentation
- ✓Genetic testing results (BRCA1/BRCA2) when performed
- ✓Treatment plan and disease status